The 4 Best CBD Suppositories in 2023

Best CBD Suppositories

Just hearing the word suppository may cause some people to cringe, but this unconventional delivery method has some definite advantages.

It provides an alternative for people experiencing nausea and vomiting who can’t keep down oral medications, have swallowing problems, or simply don’t like the taste of CBD oils or edibles. This article reveals our picks for the top five best CBD suppositories. 

Suppositories offer a method of “transmucosal absorption,” similar to dissolving a tablet under the tongue. That means that the CBD is delivered directly into the bloodstream and avoids the “first-pass effect” metabolism that occurs when CBD is taken orally. Suppositories also provide rapid absorption and onset of action.


At a Glance: The Top Four CBD Suppositories

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The 4 Best CBD Suppositories

Endoca CBD Suppositories

Endoca CBD Suppositories


  • 50 mg each
  • Discounts for bulk orders
  • Full-spectrum


  • Ingredients: Hemp extract containing phytocannabinoid cannabidiol (CBD 500mg), low concentrations of the natural forms of (CBC, CBG, CBN) Terpenes: myrcene, limonene, alpha & beta-pinene, linalool, b-caryophyllene, caryophyllene oxide, terpinolene, and humulene. Other: cannabis plant waxes, alkanes, nitrogenous compounds, amino acids, ketones, flavonoids, glycosides, vitamins, pigments, water, cofactors and co-nutrients, organic coconut oil
  • Pricing: $0.10 per milligram

Company: We chose this product for our five best CBD suppositories list because of Endoca’s overwhelmingly positive reputation. The UN has recognized the brand for its sustainable, clean, and efficient production practices, and they offer exceptional customer support, with a dedicated online chat system for questions and concerns. 

Endoca’s CBD suppositories are well-reviewed, and the brand has over 4,000 votes on Trustpilot and a rating of “excellent.” They come in a box of 10, each containing 50 milligrams of full-spectrum CBD, and can be used rectally or vaginally. Endoca claims their suppositories can increase the uptake of CBD entering the bloodstream by 10 times as opposed to a CBD capsule.

Shipping: Orders over $74 qualify for free shipping

Returns: 100% satisfaction guarantee. Contact support within 30 days.

Foria Basics Relief Suppositories with CBD

 Foria Basics Relief Suppositories with CBD


  • 100 mg each
  • Sustainably sun-grown hemp
  • Specifically designed for women


  • Ingredients: Organic-certified fair trade cocoa butter, broad-spectrum extract from USDA organic-certified, regeneratively grown USA hemp (CBD)
  • Pricing: $0.06 per milligram

Company: Foria Basics Relief Suppositories with CBD are made with only two ingredients: organic-certified fair trade cocoa butter and broad-spectrum hemp extract. Their hemp is sun-grown in the U.S. on a sustainable farm that supports biodiversity. After harvest, they use CO2 extraction to ensure a CBD rich in active cannabinoids, and the brand adheres to GMP-certified best practices throughout the manufacturing process.

Designed especially for women, the suppositories may help with menstrual cramps, muscle relaxation, pelvic and genital pain conditions, menopausal challenges, and more. Each suppository contains 100 milligrams of broad-spectrum CBD and can be used vaginally or rectally. There are no additives, preservatives, or THC. 

Shipping: Orders over $50 qualify for free shipping

Returns: Return unused products within 14 days for a refund of the purchase price minus shipping. Contact support to initiate. 

CBD Living Nano CBD Suppositories

CBD Living Nano CBD Suppositories


  • Organic nano CBD extract
  • Colorado and Oregon hemp
  • No THC


  • Ingredients: PCCA MBK™ fatty acid base, proprietary broad-spectrum nano hemp extract (aerial parts) 50 mg (cannabidiol/CBD)
  • Pricing: $0.08 per milligram

Company: Science is the driving factor behind CBD Living’s many products. The brand uses nanotechnology, which they believe is responsible for creating better, more effective CBD products. They’ve been around since 2013 and have developed a strong following in that time.

CBD Living’s Nano CBD Suppositories each contain 50 milligrams of organic nano CBD extract designed to provide possible relief from the pain and discomfort of IBS, Crohn’s, hemorrhoids, inflammation, and more. They can be used rectally or vaginally, and there are 10 suppositories in each package. It should be noted that these particular suppositories are incredibly well-reviewed. 

Shipping: Orders over $75 qualify for free shipping

Returns: Refunds are issued on a case-by-case basis. Contact support to initiate a claim.

Harmony Organic Full Spectrum Suppository

Harmony Organic Full Spectrum Suppository


  • Lower potency
  • Lab-tested
  • Made in the USA


  • Ingredients: CBD sourced from non-GMO, organic, U.S. hemp
  • Pricing: $0.29 per milligram

Company: Harmony (formerly Palmetto Harmony) began as a mother’s quest to help her child who was suffering from seizures. Today, the company has grown exponentially, offering a full range of CBD products sourced from USDA organic hemp. The brand’s offerings include tinctures, capsules, vape products, balms, and of course, these Organic Full-Spectrum CBD suppositories.

Each suppository contains 10 milligrams of CBD, so they are ideal for those looking for a less potent dose. They are full-spectrum and crafted from the brand’s own South Carolina hemp. This vertically integrated company controls all its processes from seed to sale, and each product is third-party lab tested for purity and potency before being released to the public.

Shipping: Free shipping on all U.S. orders over $99

Returns: When purchased through Direct CBD, unopened products returned within 30 days are eligible for a full refund. 

Foria Intimacy Suppositories with CBD

Foria Intimacy Suppositories with CBD


  • Enhances arousal
  • Broad-spectrum
  • Lab-tested


  • Ingredients: Organic-certified fair trade cocoa butter, broad-spectrum extract from USDA organic-certified, regeneratively-grown USA hemp (CBD)
  • Pricing: $0.10 per milligram

Company: Foria Wellness appears twice on our list, this time for the brand’s Intimacy Suppositories with CBD. They are made with the same quality process as Foria’s Relief Suppositories but are designed explicitly for making sex more comfortable and enjoyable.

There are 50 mg of broad-spectrum CBD in each suppository, and they reportedly ease discomfort, reduce tension, and enhance arousal. They contain no petroleum-based ingredients, glycerin, parabens, dyes, or phthalates and are vegan and gluten-free. For best results, insert 30 to 60 minutes before intercourse. They can also be used after sexual activity to ease soreness and discomfort and are suitable for both vaginal or rectal use.

Shipping: Orders over $50 qualify for free shipping

Returns: Return unused product within 14 days for a refund of the purchase price minus shipping. Contact support to initiate. 

What Are CBD Suppositories?

A suppository is a soft, cone-shaped medicine created to be inserted vaginally or rectally. Once placed inside the body, your body heat warms the compound, and it dissolves into the surrounding tissues. Delivering medications via suppositories is not a new thing. This method has been around for many years and is typically used for those who are too sick to swallow or keep anything down.

A CBD suppository is simply a suppository that uses CBD as an ingredient. Usually, they are made with cocoa butter, coconut oil, or some other fatty base, so they hold their shape. They are becoming more popular for potentially reducing inflammation, soothing aches and pains, and reducing tension. Since CBD is non-psychoactive, using a CBD suppository won’t get you high like a product containing THC might.

Why Use a CBD Suppository Over Other Methods?

Oral ingestion of CBD products like tinctures, oils, and capsules is fantastic, but keep in mind that when you swallow something, it needs to make the long journey through your gastrointestinal tract before it can be absorbed into the bloodstream. Additionally, the digestive process can remove some of the ingredients and potency of what you ingest, meaning it’s not always the most efficient delivery method.

On the other hand, CBD suppositories offer a method of delivery that works fast. That’s because there are many small blood vessels and cannabinoid receptors in rectal and vaginal tissue that allow the CBD to be absorbed right into the bloodstream. 

What Is the Difference Between Anal and Vaginal CBD Suppositories?

Depending on the brand and the formulation, some CBD suppositories can be inserted rectally, while others are designed for vaginal insertion. More often, they can be used both ways, and your choice will depend on the specific benefit you are looking for.

For example, you may use a CBD suppository vaginally to increase pleasure and enhance sensitivity, or to soothe irritation and discomfort during your period. Rectal suppositories may be used when taking CBD by mouth is a problem due to GI issues or difficulty swallowing. However, they may also help with hemorrhoids, IBS, and other conditions. Make sure you read the label and directions carefully before use.

Dosage of CBD Suppositories

You may have noted that many CBD suppositories contain a more potent CBD dose than oils and capsules. In most cases, you can halve or even quarter the product if the dose is too much for you. See how your body responds before using the full amount. Hint: This can also save you some cash, especially if a half-dose is sufficient to meet your needs.

Methodology: Why Are These CBD Suppositories the Best on the Market?

To determine which suppositories to include on our list, we analyze each provider for specific criteria. Here’s what we look for:

  • Third-Party Lab Testing

The first and most important factor in choosing the best CBD suppositories is whether or not the brand uses third-party lab testing for their products. An independent lab report is vital as it will reveal the exact potency, purity, and any possible contaminants in the product.

  • Clear Labeling

While not an ingestible product, suppositories still have a list of ingredients. We look for brands that state those ingredients clearly. The label should also offer dosing guidance, weight and volume, the product’s strength, and where it is made.

  • Domestic Hemp

U.S.-sourced hemp is the cleanest and safest in the world, thanks to the strict growing regulations we have in place in this country. We look for brands that source their hemp from verifiable domestic sources wherever possible.

  • Value

In this category, we look primarily at the cost per milligram, which is the fairest and most efficient way of comparing prices between brands. Compared to the sticker price, it can vary significantly.

  • Customer Service

We look at the company’s shipping and return policies, support services, and the ease of navigation of the site. After all, everyone prefers a helpful and responsive customer service staff and a hassle-free shopping experience.

  • Reputation

By now, many brands have developed their own unique reputations. Those reputations are revealed in testimonials, reviews, social media, and other places. Sometimes the best way to know whether a brand is good or not is to talk to actual users. 

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